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Palladium-Catalyzed Enantioselective Csp(3)–Csp(3) Cross-Coupling for the Synthesis of (Poly)fluorinated Chiral Building Blocks
A general method for the enantioselective synthesis of carbo- and heterocyclic carbonyl compounds bearing fluorinated α-tetrasubstituted stereocenters using palladium-catalyzed decarboxylative allylic alkylation is described. The stereoselective Csp(3) –Csp(3) cross-coupling reaction delivers five-...
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| 出版年: | Org Lett |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192028/ https://ncbi.nlm.nih.gov/pubmed/30183315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b02369 |
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