Evolution on the Biophysical Fitness Landscape of an RNA Virus

Viral evolutionary pathways are determined by the fitness landscape, which maps viral genotype to fitness. However, a quantitative description of the landscape and the evolutionary forces on it remain elusive. Here, we apply a biophysical fitness model based on capsid folding stability and antibody...

詳細記述

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書誌詳細
出版年:Mol Biol Evol
主要な著者: Rotem, Assaf, Serohijos, Adrian W R, Chang, Connie B, Wolfe, Joshua T, Fischer, Audrey E, Mehoke, Thomas S, Zhang, Huidan, Tao, Ye, Lloyd Ung, W, Choi, Jeong-Mo, Rodrigues, João V, Kolawole, Abimbola O, Koehler, Stephan A, Wu, Susan, Thielen, Peter M, Cui, Naiwen, Demirev, Plamen A, Giacobbi, Nicholas S, Julian, Timothy R, Schwab, Kellogg, Lin, Jeffrey S, Smith, Thomas J, Pipas, James M, Wobus, Christiane E, Feldman, Andrew B, Weitz, David A, Shakhnovich, Eugene I
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
Discoveries
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188569/
https://ncbi.nlm.nih.gov/pubmed/29955873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msy131
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