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Protein Biophysics Explains Why Highly Abundant Proteins Evolve Slowly

The consistent observation across all kingdoms of life that highly abundant proteins evolve slowly demonstrates that cellular abundance is a key determinant of protein evolutionary rate. However, other empirical findings, such as the broad distribution of evolutionary rates, suggest that additional...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Serohijos, Adrian W.R., Rimas, Zilvinas, Shakhnovich, Eugene I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533372/
https://ncbi.nlm.nih.gov/pubmed/22938865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.06.022
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