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Highly Abundant Proteins Favor More Stable 3D Structures in Yeast

To understand the variation of protein sequences in nature, we need to reckon with evolutionary constraints that are biophysical, cellular, and ecological. Here, we show that under the global selection against protein misfolding, there exists a scaling among protein folding stability, protein cellul...

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Detalhes bibliográficos
Main Authors: Serohijos, Adrian W.R., Lee, S. Y. Ryan, Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566449/
https://ncbi.nlm.nih.gov/pubmed/23442924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.11.3838
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