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Highly Abundant Proteins Favor More Stable 3D Structures in Yeast

To understand the variation of protein sequences in nature, we need to reckon with evolutionary constraints that are biophysical, cellular, and ecological. Here, we show that under the global selection against protein misfolding, there exists a scaling among protein folding stability, protein cellul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Serohijos, Adrian W.R., Lee, S. Y. Ryan, Shakhnovich, Eugene I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566449/
https://ncbi.nlm.nih.gov/pubmed/23442924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.11.3838
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