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Contribution of Selection for Protein Folding Stability in Shaping the Patterns of Polymorphisms in Coding Regions

The patterns of polymorphisms in genomes are imprints of the evolutionary forces at play in nature. In particular, polymorphisms have been extensively used to infer the fitness effects of mutations and their dynamics of fixation. However, the role and contribution of molecular biophysics to these ob...

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Detaylı Bibliyografya
Asıl Yazarlar: Serohijos, Adrian W.R., Shakhnovich, Eugene I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879451/
https://ncbi.nlm.nih.gov/pubmed/24124208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst189
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