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Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly

The cause of the tremendous among-protein variation in the rate of sequence evolution is a central subject of molecular evolution. Expression level has been identified as a leading determinant of this variation among genes encoded in the same genome, but the underlying mechanisms are not fully under...

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Detalhes bibliográficos
Main Authors: Park, Chungoo, Chen, Xiaoshu, Yang, Jian-Rong, Zhang, Jianzhi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581962/
https://ncbi.nlm.nih.gov/pubmed/23382244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218066110
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