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Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
The tempo and mode of protein evolution have been central questions in biology. Genomic data have shown a strong influence of the expression level of a protein on its rate of sequence evolution (E-R anticorrelation), which is currently explained by the protein misfolding avoidance hypothesis. Here,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325723/ https://ncbi.nlm.nih.gov/pubmed/22416125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117408109 |
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