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Evolutionary dynamics of viral escape under antibodies stress: A biophysical model

Viruses constantly face the selection pressure of antibodies, either from innate immune response of the host or from administered antibodies for treatment. We explore the interplay between the biophysical properties of viral proteins and the population and demographic variables in the viral escape....

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Detalles Bibliográficos
Publicado en:Protein Sci
Main Authors: Chéron, Nicolas, Serohijos, Adrian W.R., Choi, Jeong‐Mo, Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4918420/
https://ncbi.nlm.nih.gov/pubmed/26939576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2915
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