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The Role of Evolutionary Selection in the Dynamics of Protein Structure Evolution

Homology modeling is a powerful tool for predicting a protein’s structure. This approach is successful because proteins whose sequences are only 30% identical still adopt the same structure, while structure similarity rapidly deteriorates beyond the 30% threshold. By studying the divergence of prote...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Gilson, Amy I., Marshall-Christensen, Ahmee, Choi, Jeong-Mo, Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390048/
https://ncbi.nlm.nih.gov/pubmed/28402878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.029
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