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Evolution of Specificity in Protein-Protein Interactions

Hub proteins are proteins that maintain promiscuous molecular recognition. Because they are reported to play essential roles in cellular control, there has been a special interest in the study of their structural and functional properties, yet the mechanisms by which they evolve to maintain function...

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Detalhes bibliográficos
Main Authors: Peleg, Orit, Choi, Jeong-Mo, Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190652/
https://ncbi.nlm.nih.gov/pubmed/25296322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.004
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