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CYP51 as drug targets for fungi and protozoan parasites: past, present and future

The efficiency of treatment of human infections with the unicellular eukaryotic pathogens such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates from nosocomial fungemia in critically ill, immunosuppressed or post cancer patients often exceed 50%. A set of six sys...

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Vydáno v:Parasitology
Hlavní autoři: Lepesheva, Galina I., Friggeri, Laura, Waterman, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185833/
https://ncbi.nlm.nih.gov/pubmed/29642960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0031182018000562
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