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CYP51 as drug targets for fungi and protozoan parasites: past, present and future

The efficiency of treatment of human infections with the unicellular eukaryotic pathogens such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates from nosocomial fungemia in critically ill, immunosuppressed or post cancer patients often exceed 50%. A set of six sys...

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Bibliografiske detaljer
Udgivet i:Parasitology
Main Authors: Lepesheva, Galina I., Friggeri, Laura, Waterman, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185833/
https://ncbi.nlm.nih.gov/pubmed/29642960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0031182018000562
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