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Structural basis for conservation in the CYP51 family

Sterol 14α-demethylases (14DM) comprise the CYP51 cytochrome P450 genome family. The 14DM reaction is essential for the biosynthesis of sterols which are necessary for production of cellular membranes. This is the most widely distributed P450, being present in all biological kingdoms. From one kingd...

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Detalhes bibliográficos
Main Authors: Lepesheva, Galina I., Waterman, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962772/
https://ncbi.nlm.nih.gov/pubmed/20547249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2010.06.006
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