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Targeting Trypanosoma cruzi Sterol 14α-Demethylase (CYP51)
There are at least two obvious features that must be considered upon targeting specific metabolic pathways/enzymes for drug development: the pathway must be essential and the enzyme must allow the design of pharmacologically useful inhibitors. Here, we describe Trypanosoma cruzi sterol 14α-demethyla...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488290/ https://ncbi.nlm.nih.gov/pubmed/21820552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-385863-4.00004-6 |
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