Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Δ7-24, 25-dihydrolanosterol

Sterol 14α-demethylase (CYP51) that catalyzes the removal of the 14α-methyl group from the sterol nucleus is an essential enzyme in sterol biosynthesis, a primary target for clinical and agricultural antifungal azoles and an emerging target for antitrypanosomal chemotherapy. Here, we present the cry...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Hargrove, Tatiana Y., Wawrzak, Zdzislaw, Liu, Jialin, Waterman, Michael R., Nes, W. David, Lepesheva, Galina I.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2012
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269163/
https://ncbi.nlm.nih.gov/pubmed/22135275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021865
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki