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CYP51 as drug targets for fungi and protozoan parasites: past, present and future

The efficiency of treatment of human infections with the unicellular eukaryotic pathogens such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates from nosocomial fungemia in critically ill, immunosuppressed or post cancer patients often exceed 50%. A set of six sys...

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Detalhes bibliográficos
Publicado no:Parasitology
Main Authors: Lepesheva, Galina I., Friggeri, Laura, Waterman, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6185833/
https://ncbi.nlm.nih.gov/pubmed/29642960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0031182018000562
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