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CYP51: A Major Drug Target in the Cytochrome P450 Superfamily

The cytochrome P540 (CYP) superfamily currently includes about 9,000 proteins forming more than 800 families. The enzymes catalyze monooxygenation of a vast array of compounds and play essentially two roles. They provide biodefense (detoxification of xenobiotics, antibiotic production) and participa...

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Main Authors: Lepesheva, Galina I., Hargrove, Tatyana Y., Kleshchenko, Yuliya, Nes, W. David, Villalta, Fernando, Waterman, Michael R.
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715142/
https://ncbi.nlm.nih.gov/pubmed/18769951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-008-3225-y
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