Nalaganje...
NAD(+)-dependent synthesis of a 5′-phospho-ADP-ribosylated RNA/DNA cap by RNA 2′-phosphotransferase Tpt1
RNA 2′-phosphotransferase Tpt1 converts an internal RNA 2′-monophosphate to a 2′-OH via a two-step NAD(+)-dependent mechanism in which: (i) the 2′-phosphate attacks the C1″ of NAD(+) to expel nicotinamide and form a 2′-phospho-ADP-ribosylated RNA intermediate; and (ii) the ADP-ribose O2″ attacks the...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2018
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6182162/ https://ncbi.nlm.nih.gov/pubmed/30202863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky792 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|