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Structure–function analysis of the yeast NAD(+)-dependent tRNA 2′-phosphotransferase Tpt1

Tpt1 is an essential 230-amino-acid enzyme that catalyzes the final step in yeast tRNA splicing: the transfer of the 2′-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1″-2″cyclic phosphate and nicotinamide. To understand the structural requirements for Saccharomyces cerevisiae Tpt1 acti...

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Detalhes bibliográficos
Main Authors: SAWAYA, RANA, SCHWER, BEATE, SHUMAN, STEWART
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2005 by RNA Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370696/
https://ncbi.nlm.nih.gov/pubmed/15611301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7193705
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