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Structure–function analysis of the kinase-CPD domain of yeast tRNA ligase (Trl1) and requirements for complementation of tRNA splicing by a plant Trl1 homolog

Trl1 is an essential 827 amino acid enzyme that executes the end-healing and end-sealing steps of tRNA splicing in Saccharomyces cerevisiae. Trl1 consists of two domains—an N-terminal ligase component and a C-terminal 5′-kinase/2′,3′-cyclic phosphodiesterase (CPD) component—that can function in tRNA...

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Bibliografische gegevens
Hoofdauteurs: Wang, Li Kai, Schwer, Beate, Englert, Markus, Beier, Hildburg, Shuman, Stewart
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345694/
https://ncbi.nlm.nih.gov/pubmed/16428247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj441
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