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Human RNA 5′-kinase (hClp1) can function as a tRNA splicing enzyme in vivo
Yeast and human Clp1 proteins are homologous components of the mRNA 3′-cleavage-polyadenylation machinery. Recent studies highlighting an association of human Clp1 (hClp1) with tRNA splicing endonuclease and an intrinsic RNA-specific 5′-OH polynucleotide kinase activity of hClp1 have prompted specul...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525948/ https://ncbi.nlm.nih.gov/pubmed/18648070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1142908 |
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