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Human RNA 5′-kinase (hClp1) can function as a tRNA splicing enzyme in vivo

Yeast and human Clp1 proteins are homologous components of the mRNA 3′-cleavage-polyadenylation machinery. Recent studies highlighting an association of human Clp1 (hClp1) with tRNA splicing endonuclease and an intrinsic RNA-specific 5′-OH polynucleotide kinase activity of hClp1 have prompted specul...

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Detalhes bibliográficos
Main Authors: Ramirez, Alejandro, Shuman, Stewart, Schwer, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525948/
https://ncbi.nlm.nih.gov/pubmed/18648070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1142908
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