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Mammalian 2′,3′ cyclic nucleotide phosphodiesterase (CNP) can function as a tRNA splicing enzyme in vivo

Yeast and plant tRNA splicing entails discrete healing and sealing steps catalyzed by a tRNA ligase that converts the 2′,3′ cyclic phosphate and 5′-OH termini of the broken tRNA exons to 3′-OH/2′-PO(4) and 5′-PO(4) ends, respectively, then joins the ends to yield a 2′-PO(4), 3′-5′ phosphodiester spl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schwer, Beate, Aronova, Anna, Ramirez, Alejandro, Braun, Peter, Shuman, Stewart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212240/
https://ncbi.nlm.nih.gov/pubmed/18094118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.858108
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