Pharmacological characterization of levorphanol, a G-protein biased opioid analgesic

BACKGROUND: Levorphanol is a potent analgesic that has been used for decades. Most commonly used for acute and cancer pain, it also is effective against neuropathic pain. The recent appreciation of the importance of functional bias and the uncovering of multiple mu opioid receptor splice variants ma...

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Vydáno v:Anesth Analg
Hlavní autoři: Le Rouzic, Valerie, Narayan, Ankita, Hunkle, Amanda, Marrone, Gina F., Lu, Zhigang, Majumdar, Susruta, Xu, Jin, Pan, Ying-Xian, Pasternak, Gavril W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181797/
https://ncbi.nlm.nih.gov/pubmed/29649035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000003360
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