Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2

The Gcn5 histone acetyltransferase (HAT) subunit of the SAGA transcriptional coactivator complex catalyzes acetylation of histone H3 and H2B N-terminal tails, posttranslational modifications associated with gene activation. Binding of the SAGA subunit partner Ada2 to Gcn5 activates Gcn5’s intrinsica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Sun, Jian, Paduch, Marcin, Kim, Sang-Ah, Kramer, Ryan M., Barrios, Adam F., Lu, Vincent, Luke, Judy, Usatyuk, Svitlana, Kossiakoff, Anthony A., Tan, Song
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176591/
https://ncbi.nlm.nih.gov/pubmed/30224453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805343115
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg