DNA Binding by Sgf11 Protein Affects Histone H2B Deubiquitination by Spt-Ada-Gcn5-Acetyltransferase (SAGA)

The yeast Spt-Ada-Gcn5-acetyltransferase (SAGA) complex is a transcription coactivator that contains a histone H2B deubiquitination activity mediated by its Ubp8 subunit. Full enzymatic activity requires the formation of a quaternary complex, the deubiquitination module (DUBm) of SAGA, which is comp...

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Bibliographic Details
Main Authors: Koehler, Christian, Bonnet, Jacques, Stierle, Matthieu, Romier, Christophe, Devys, Didier, Kieffer, Bruno
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979380/
https://ncbi.nlm.nih.gov/pubmed/24509845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.500868
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