Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5

Histone acetyl transferases (HATs) play a crucial role in eukaryotes by regulating chromatin architecture and locus specific transcription. GCN5 (KAT2A) is a member of the GNAT (Gcn5-related N-acetyltransferase) family of HATs. In metazoans this enzyme is found in two functionally distinct coactivat...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Riss, Anne, Scheer, Elisabeth, Joint, Mathilde, Trowitzsch, Simon, Berger, Imre, Tora, László
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661412/
https://ncbi.nlm.nih.gov/pubmed/26468280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.668533
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