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Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2

The Gcn5 histone acetyltransferase (HAT) subunit of the SAGA transcriptional coactivator complex catalyzes acetylation of histone H3 and H2B N-terminal tails, posttranslational modifications associated with gene activation. Binding of the SAGA subunit partner Ada2 to Gcn5 activates Gcn5’s intrinsica...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Sun, Jian, Paduch, Marcin, Kim, Sang-Ah, Kramer, Ryan M., Barrios, Adam F., Lu, Vincent, Luke, Judy, Usatyuk, Svitlana, Kossiakoff, Anthony A., Tan, Song
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176591/
https://ncbi.nlm.nih.gov/pubmed/30224453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805343115
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