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Reviving oncogenic addiction to MET bypassed by BRAF (G469A) mutation

Cancer clonal evolution is based on accrual of driving genetic alterations that are expected to cooperate and progressively increase malignancy. Little is known on whether any genetic alteration can hinder the oncogenic function of a coexisting alteration, so that therapeutic targeting of the one ca...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Virzì, Anna Rita, Gentile, Alessandra, Benvenuti, Silvia, Comoglio, Paolo M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176587/
https://ncbi.nlm.nih.gov/pubmed/30224486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721147115
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