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Reviving oncogenic addiction to MET bypassed by BRAF (G469A) mutation

Cancer clonal evolution is based on accrual of driving genetic alterations that are expected to cooperate and progressively increase malignancy. Little is known on whether any genetic alteration can hinder the oncogenic function of a coexisting alteration, so that therapeutic targeting of the one ca...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Virzì, Anna Rita, Gentile, Alessandra, Benvenuti, Silvia, Comoglio, Paolo M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176587/
https://ncbi.nlm.nih.gov/pubmed/30224486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721147115
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