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Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction

Oncogene addiction is a cellular property by which cancer cells become highly dependent on the expression of oncogenes for their survival. Oncogene addiction can be exploited to design molecularly targeted drugs that kill only cancer cells by inhibiting the specific oncogenes. Genes and cell lines e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ito, Reina E., Oneyama, Chitose, Aoki, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016361/
https://ncbi.nlm.nih.gov/pubmed/33793658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249388
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