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Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction

Oncogene addiction is a cellular property by which cancer cells become highly dependent on the expression of oncogenes for their survival. Oncogene addiction can be exploited to design molecularly targeted drugs that kill only cancer cells by inhibiting the specific oncogenes. Genes and cell lines e...

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Vydáno v:PLoS One
Hlavní autoři: Ito, Reina E., Oneyama, Chitose, Aoki, Kazuhiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016361/
https://ncbi.nlm.nih.gov/pubmed/33793658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0249388
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