KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia

The prognostic value of RAS mutations has been systematically investigated in acute myeloid leukemia (AML). However, clinical significance of RAS expressions in AML remains poorly determined. To explore the clinical significance, we analyzed KRAS and NRAS expressions in 143 de novo AML patients by r...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhou, Jing-Dong, Yao, Dong-Ming, Li, Xi-Xi, Zhang, Ting-Juan, Zhang, Wei, Ma, Ji-Chun, Guo, Hong, Deng, Zhao-Qun, Lin, Jiang, Qian, Jun
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630394/
https://ncbi.nlm.nih.gov/pubmed/29029494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19798
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