KRAS overexpression independent of RAS mutations confers an adverse prognosis in cytogenetically normal acute myeloid leukemia

The prognostic value of RAS mutations has been systematically investigated in acute myeloid leukemia (AML). However, clinical significance of RAS expressions in AML remains poorly determined. To explore the clinical significance, we analyzed KRAS and NRAS expressions in 143 de novo AML patients by r...

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Udgivet i:Oncotarget
Main Authors: Zhou, Jing-Dong, Yao, Dong-Ming, Li, Xi-Xi, Zhang, Ting-Juan, Zhang, Wei, Ma, Ji-Chun, Guo, Hong, Deng, Zhao-Qun, Lin, Jiang, Qian, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630394/
https://ncbi.nlm.nih.gov/pubmed/29029494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19798
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