Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS

Hyperpolarized [1‐(13)C] pyruvate MRS can measure cardiac pyruvate dehydrogenase (PDH) flux in vivo through (13)C‐label incorporation into bicarbonate. Using this technology, substrate availability as well as pathology have been shown to modulate PDH flux. Clinical protocols attempt to standardize P...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:NMR Biomed
मुख्य लेखकों: Timm, Kerstin N., Apps, Andrew, Miller, Jack J., Ball, Vicky, Chong, Cher‐Rin, Dodd, Michael S., Tyler, Damian J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2018
विषय:
Research Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175301/
https://ncbi.nlm.nih.gov/pubmed/30040147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3992
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