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In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

The advent of hyperpolarized (13)C magnetic resonance (MR) has provided new potential for the real-time visualization of in vivo metabolic processes. The aim of this work was to use hyperpolarized [1-(13)C]pyruvate as a metabolic tracer to assess noninvasively the flux through the mitochondrial enzy...

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Hlavní autoři: Schroeder, Marie A., Cochlin, Lowri E., Heather, Lisa C., Clarke, Kieran, Radda, George K., Tyler, Damian J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515222/
https://ncbi.nlm.nih.gov/pubmed/18689683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805953105
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