The Role of AMPK Activation for Cardioprotection in Doxorubicin-Induced Cardiotoxicity

Por Timm, Kerstin N., Tyler, Damian J.
Publicado no Cardiovasc Drugs Ther (2020)

Imaging Tumor Metabolism to Assess Disease Progression and Treatment Response

Por Timm, Kerstin N., Kennedy, Brett W.C., Brindle, Kevin M.
Publicado no Clin Cancer Res (2016)

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS

Por Timm, Kerstin N., Apps, Andrew, Miller, Jack J., Ball, Vicky, Chong, Cher‐Rin, Dodd, Michael S., Tyler, Damian J.
Publicado no NMR Biomed (2018)

A 3D hybrid-shot spiral sequence for hyperpolarized (13)C imaging

Por Tyler, Andrew, Lau, Justin Y. C., Ball, Vicky, Timm, Kerstin N., Zhou, Tony, Tyler, Damian J., Miller, Jack J.
Publicado no Magn Reson Med (2021)

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol

Por Kerr, Matthew, Miller, Jack J., Thapa, Dharendra, Stiewe, Sophie, Timm, Kerstin N., Aparicio, Claudia N. Montes, Scott, Iain, Tyler, Damian J., Heather, Lisa C.
Publicado no JCI Insight (2020)

Probing hepatic metabolism of [2-(13)C]dihydroxyacetone in vivo with (1)H-decoupled hyperpolarized (13)C-MR

Por Marco-Rius, Irene, Wright, Alan J., Hu, De-en, Savic, Dragana, Miller, Jack J., Timm, Kerstin N., Tyler, Damian, Brindle, Kevin M., Comment, Arnaud
Publicado no MAGMA (2020)

L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI

Por Savic, Dragana, Ball, Vicky, Curtis, M. Kate, Sousa Fialho, Maria da Luz, Timm, Kerstin N., Hauton, David, West, James, Griffin, Julian, Heather, Lisa C., Tyler, Damian J.
Publicado no Metabolites (2021)

Rapid, [Formula: see text] ‐insensitive, dual‐band quasi‐adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux

Por Miller, Jack J., Valkovič, Ladislav, Kerr, Matthew, Timm, Kerstin N., Watson, William D., Lau, Justin Y. C., Tyler, Andrew, Rodgers, Christopher, Bottomley, Paul A., Heather, Lisa C., Tyler, Damian J.
Publicado no Magn Reson Med (2021)

Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-(13)C]Dehydroascorbic Acid Reduction Using (13)C Magnetic Resonance Spectroscopy

Por Timm, Kerstin N., Hu, De-En, Williams, Michael, Wright, Alan J., Kettunen, Mikko I., Kennedy, Brett W. C., Larkin, Timothy J., Dzien, Piotr, Marco-Rius, Irene, Bohndiek, Sarah E., Brindle, Kevin M.
Publicado no J Biol Chem (2017)

Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse

Por Marco-Rius, Irene, Tayler, Michael C D, Kettunen, Mikko I, Larkin, Timothy J, Timm, Kerstin N, Serrao, Eva M, Rodrigues, Tiago B, Pileio, Giuseppe, Ardenkjaer-Larsen, Jan Henrik, Levitt, Malcolm H, Brindle, Kevin M
Publicado no NMR Biomed (2013)

Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes

Por Dodd, Michael S., Sousa Fialho, Maria da Luz, Montes Aparicio, Claudia N., Kerr, Matthew, Timm, Kerstin N., Griffin, Julian L., Luiken, Joost J.F.P., Glatz, Jan F.C., Tyler, Damian J., Heather, Lisa C.
Publicado no JACC Basic Transl Sci (2018)

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI

Por Timm, Kerstin N., Perera, Charith, Ball, Vicky, Henry, John A., Miller, Jack J., Kerr, Matthew, West, James A., Sharma, Eshita, Broxholme, John, Logan, Angela, Savic, Dragana, Dodd, Michael S., Griffin, Julian L., Murphy, Michael P., Heather, Lisa C., Tyler, Damian J.
Publicado no Commun Biol (2020)

(13)C magnetic resonance spectroscopy measurements with hyperpolarized [1‐(13)C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo...

Por Dzien, Piotr, Tee, Sui‐Seng, Kettunen, Mikko I., Lyons, Scott K., Larkin, Timothy J., Timm, Kerstin N., Hu, De‐En, Wright, Alan, Rodrigues, Tiago B., Serrao, Eva M., Marco‐Rius, Irene, Mannion, Elizabeth, D'Santos, Paula, Kennedy, Brett W. C., Brindle, Kevin M.
Publicado no Magn Reson Med (2015)