Probing hepatic metabolism of [2-(13)C]dihydroxyacetone in vivo with (1)H-decoupled hyperpolarized (13)C-MR

OBJECTIVES: To enhance detection of the products of hyperpolarized [2-(13)C]dihydroxyacetone metabolism for assessment of three metabolic pathways in the liver in vivo. Hyperpolarized [2-(13)C]DHAc emerged as a promising substrate to follow gluconeogenesis, glycolysis and the glycerol pathways. Howe...

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Detalhes bibliográficos
Publicado no:MAGMA
Main Authors: Marco-Rius, Irene, Wright, Alan J., Hu, De-en, Savic, Dragana, Miller, Jack J., Timm, Kerstin N., Tyler, Damian, Brindle, Kevin M., Comment, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910257/
https://ncbi.nlm.nih.gov/pubmed/32910316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10334-020-00884-y
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