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(13)C magnetic resonance spectroscopy measurements with hyperpolarized [1‐(13)C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo
PURPOSE: Dissolution dynamic nuclear polarization can increase the sensitivity of the (13)C magnetic resonance spectroscopy experiment by at least four orders of magnitude and offers a novel approach to the development of MRI gene reporters based on enzymes that metabolize (13)C‐labeled tracers. We...
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| Wydane w: | Magn Reson Med |
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| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
John Wiley and Sons Inc.
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025726/ https://ncbi.nlm.nih.gov/pubmed/26388418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25879 |
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