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Kinetic Modeling of Hyperpolarized (13)C Label Exchange between Pyruvate and Lactate in Tumor Cells

Measurements of the kinetics of hyperpolarized (13)C label exchange between [1-(13)C]pyruvate and lactate in suspensions of intact and lysed murine lymphoma cells, and in cells in which lactate dehydrogenase expression had been modulated by inhibition of the PI3K pathway, were used to determine quan...

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書誌詳細
主要な著者: Witney, Timothy H., Kettunen, Mikko I., Brindle, Kevin M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137032/
https://ncbi.nlm.nih.gov/pubmed/21596745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237727
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