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Kinetic Modeling of Hyperpolarized (13)C Label Exchange between Pyruvate and Lactate in Tumor Cells

Measurements of the kinetics of hyperpolarized (13)C label exchange between [1-(13)C]pyruvate and lactate in suspensions of intact and lysed murine lymphoma cells, and in cells in which lactate dehydrogenase expression had been modulated by inhibition of the PI3K pathway, were used to determine quan...

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Bibliografische gegevens
Hoofdauteurs: Witney, Timothy H., Kettunen, Mikko I., Brindle, Kevin M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137032/
https://ncbi.nlm.nih.gov/pubmed/21596745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237727
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