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Comparison of Kinetic Models for Analysis of Pyruvate-to-Lactate Exchange by Hyperpolarized (13)C NMR

The activity of specific enzyme-catalyzed reactions may be detected in vivo by (13)C NMR of hyperpolarized (HP) substrates. The signal from HP substrates and products, acquired over time, have been fit to a number of different mathematical models to determine fluxes, but these models have not been c...

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Autori principali: Harrison, Crystal, Yang, Chendong, Jindal, Ashish, DeBerardinis, Ralph J., Hooshyar, M.A., Merritt, Matthew, Sherry, A. Dean, Malloy, Craig R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469722/
https://ncbi.nlm.nih.gov/pubmed/22451442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2801
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