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Simultaneous Steady-state and Dynamic (13)C NMR Can Differentiate Alternative Routes of Pyruvate Metabolism in Living Cancer Cells
Metabolic reprogramming facilitates cancer cell growth, so quantitative metabolic flux measurements could produce useful biomarkers. However, current methods to analyze flux in vivo provide either a steady-state overview of relative activities (infusion of (13)C and analysis of extracted metabolites...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3937686/ https://ncbi.nlm.nih.gov/pubmed/24415759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543637 |
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