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Active Pyruvate Dehydrogenase and Impaired Gluconeogenesis in Orthotopic Hepatomas of Rats
BACKGROUND: Therapies targeting altered activity of pyruvate dehydrogenase (PDH) and pyruvate carboxylase (PC) have been proposed for hepatomas. However, the activities of these pathways in hepatomas in vivo have not been distinguished. Here we examined pyruvate entry into the tricarboxylic acid (TC...
में बचाया:
| में प्रकाशित: | Metabolism |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6892165/ https://ncbi.nlm.nih.gov/pubmed/31672442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2019.153993 |
| टैग : |
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