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Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS
Hyperpolarized [1‐(13)C] pyruvate MRS can measure cardiac pyruvate dehydrogenase (PDH) flux in vivo through (13)C‐label incorporation into bicarbonate. Using this technology, substrate availability as well as pathology have been shown to modulate PDH flux. Clinical protocols attempt to standardize P...
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| Pubblicato in: | NMR Biomed |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6175301/ https://ncbi.nlm.nih.gov/pubmed/30040147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3992 |
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