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Rational Design and Screening of Peptide-Based Inhibitors of Heat Shock Factor 1 (HSF1)
Heat shock factor 1 (HSF1) is a stress-responsive transcription factor that regulates expression of protein chaperones and cell survival factors. In cancer, HSF1 plays a unique role, hijacking the normal stress response to drive a cancer-specific transcriptional program. These observations suggest t...
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| Publicado en: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6174099/ https://ncbi.nlm.nih.gov/pubmed/29661622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.04.018 |
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