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Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity
The heat shock transcription factor 1 (HSF1) activates expression of a variety of genes involved in cell survival, including protein chaperones, the protein degradation machinery, anti-apoptotic proteins, and transcription factors. Although HSF1 activation has been linked to amelioration of neurodeg...
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Main Authors: | , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215228/ https://ncbi.nlm.nih.gov/pubmed/25204655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591578 |
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