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Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases

Neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis and prion-based neurodegeneration are associated with the accumulation of misfolded proteins, resulting in neuronal dysfunction and cell death. However, current treatments...

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Detalhes bibliográficos
Main Authors: Neef, Daniel W., Jaeger, Alex M., Thiele, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518299/
https://ncbi.nlm.nih.gov/pubmed/22129991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3453
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