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Regulation of heat shock transcription factors and their roles in physiology and disease

The heat shock transcription factors (HSFs) were discovered over 30 years ago as direct transcriptional activators of genes regulated by thermal stress, encoding heat shock proteins. The accepted paradigm posited that HSFs exclusively activate the expression of protein chaperones in response to cond...

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Bibliografische gegevens
Gepubliceerd in:Nat Rev Mol Cell Biol
Hoofdauteurs: Gomez-Pastor, Rocio, Burchfiel, Eileen T., Thiele, Dennis J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794010/
https://ncbi.nlm.nih.gov/pubmed/28852220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2017.73
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