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Regulation of heat shock transcription factors and their roles in physiology and disease

The heat shock transcription factors (HSFs) were discovered over 30 years ago as direct transcriptional activators of genes regulated by thermal stress, encoding heat shock proteins. The accepted paradigm posited that HSFs exclusively activate the expression of protein chaperones in response to cond...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Rev Mol Cell Biol
Prif Awduron: Gomez-Pastor, Rocio, Burchfiel, Eileen T., Thiele, Dennis J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794010/
https://ncbi.nlm.nih.gov/pubmed/28852220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2017.73
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