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Genomic Heat Shock Element Sequences Drive Cooperative Human Heat Shock Factor 1 DNA Binding and Selectivity

The heat shock transcription factor 1 (HSF1) activates expression of a variety of genes involved in cell survival, including protein chaperones, the protein degradation machinery, anti-apoptotic proteins, and transcription factors. Although HSF1 activation has been linked to amelioration of neurodeg...

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Autors principals: Jaeger, Alex M., Makley, Leah N., Gestwicki, Jason E., Thiele, Dennis J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215228/
https://ncbi.nlm.nih.gov/pubmed/25204655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.591578
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