Mcp1 Promotes Macrophage-Dependent Cyst Expansion in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND: In patients with autosomal dominant polycystic kidney disease (ADPKD), most of whom have a mutation in PKD1 or PKD2, abnormally large numbers of macrophages accumulate around kidney cysts and promote their growth. Research by us and others has suggested that monocyte chemoattractant prot...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Am Soc Nephrol
Hlavní autoři: Cassini, Marcelo F., Kakade, Vijayakumar R., Kurtz, Elizabeth, Sulkowski, Parker, Glazer, Peter, Torres, Richard, Somlo, Stefan, Cantley, Lloyd G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2018
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171277/
https://ncbi.nlm.nih.gov/pubmed/30209078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018050518
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky