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Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease

The primary cilium of renal epithelia acts as a transducer of extracellular stimuli. Polycystin (PC)1 is the protein encoded by the PKD1 gene that is responsible for the most common and severe form of autosomal dominant polycystic kidney disease (ADPKD). PC1 forms a complex with PC2 via their respec...

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Detalhes bibliográficos
Publicado no:Kidney Res Clin Pract
Main Authors: Lee, Seung Hun, Somlo, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714135/
https://ncbi.nlm.nih.gov/pubmed/26877954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.krcp.2014.05.002
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